Residues crucial for Ras interaction with GDP-GTP exchangers.

Cdc25 is essential for Ras-mediated activation of adenylyl cyclase in the yeast Saccharomyces cerevisiae. This protein acts by catalyzing GDP-GTP exchange on yeast Ras. Harvey (Ha) ras expressed in S. cerevisiae is also recognized by both Cdc25 and Sdc25, a yeast homolog of Cdc25. Thus it is feasibl...

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Detalles Bibliográficos
Main Authors: Segal, M, Willumsen, B M, Levitzki, A
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC46761/
https://ncbi.nlm.nih.gov/pubmed/8516302
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