Residues crucial for Ras interaction with GDP-GTP exchangers.

Cdc25 is essential for Ras-mediated activation of adenylyl cyclase in the yeast Saccharomyces cerevisiae. This protein acts by catalyzing GDP-GTP exchange on yeast Ras. Harvey (Ha) ras expressed in S. cerevisiae is also recognized by both Cdc25 and Sdc25, a yeast homolog of Cdc25. Thus it is feasibl...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Segal, M, Willumsen, B M, Levitzki, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8516302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.12.5564
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