Carregando...
Conformational Transitions in Human AP Endonuclease 1 and Its Active Site Mutant during Abasic Site Repair
AP endonuclease 1 (APE 1) is a crucial enzyme of the base excision repair pathway (BER) in human cells. APE1 recognizes apurinic/apyrimidinic (AP) sites and makes a nick in the phosphodiester backbone 5′ to them. The conformational dynamics and presteady-state kinetics of wild-type APE1 and its acti...
Na minha lista:
| Publicado no: | Biochemistry |
|---|---|
| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676079/ https://ncbi.nlm.nih.gov/pubmed/20575528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100769k |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|