Nonenzymatic release of N7-methylguanine channels repair of abasic sites into an AP endonuclease-independent pathway in Arabidopsis

Abasic (apurinic/apyrimidinic, AP) sites in DNA arise from spontaneous base loss or by enzymatic removal during base excision repair. It is commonly accepted that both classes of AP site have analogous biochemical properties and are equivalent substrates for AP endonucleases and AP lyases, although...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Barbado, Casimiro, Córdoba-Cañero, Dolores, Ariza, Rafael R., Roldán-Arjona, Teresa
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798382/
https://ncbi.nlm.nih.gov/pubmed/29339505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719497115
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