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Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data
Motivation: Targeted kinase inhibitors have dramatically improved cancer treatment, but kinase dependency for an individual patient or cancer cell can be challenging to predict. Kinase dependency does not always correspond with gene expression and mutation status. High-throughput drug screens are po...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675831/ https://ncbi.nlm.nih.gov/pubmed/26206305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv427 |
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