Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe–S Assembly Complex

[Image: see text] Iron–sulfur (Fe–S) clusters function as protein cofactors for a wide variety of critical cellular reactions. In human mitochondria, a core Fe–S assembly complex [called SDUF and composed of NFS1, ISD11, ISCU2, and frataxin (FXN) proteins] synthesizes Fe–S clusters from iron, cystei...

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Publicado en:Biochemistry
Main Authors: Fox, Nicholas G., Das, Deepika, Chakrabarti, Mrinmoy, Lindahl, Paul A., Barondeau, David P.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675465/
https://ncbi.nlm.nih.gov/pubmed/26016518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5014497
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