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Mechanism of frataxin “bypass” in human iron–sulfur cluster biosynthesis with implications for Friedreich's ataxia

In humans, mitochondrial iron–sulfur cluster biosynthesis is an essential biochemical process mediated by the assembly complex consisting of cysteine desulfurase (NFS1), LYR protein (ISD11), acyl-carrier protein (ACP), and the iron–sulfur cluster assembly scaffold protein (ISCU2). The protein fratax...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Das, Deepika, Patra, Shachin, Bridwell-Rabb, Jennifer, Barondeau, David P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556584/
https://ncbi.nlm.nih.gov/pubmed/30975898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007716
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