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Mechanism of frataxin “bypass” in human iron–sulfur cluster biosynthesis with implications for Friedreich's ataxia
In humans, mitochondrial iron–sulfur cluster biosynthesis is an essential biochemical process mediated by the assembly complex consisting of cysteine desulfurase (NFS1), LYR protein (ISD11), acyl-carrier protein (ACP), and the iron–sulfur cluster assembly scaffold protein (ISCU2). The protein fratax...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6556584/ https://ncbi.nlm.nih.gov/pubmed/30975898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007716 |
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