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Functional redundancy of transcription factors explains why most binding targets of a transcription factor are not affected when the transcription factor is knocked out

BACKGROUND: Biologists are puzzled by the extremely low percentage (3%) of the binding targets of a yeast transcription factor (TF) affected when the TF is knocked out, a phenomenon observed by comparing the TF binding dataset and TF knockout effect dataset. RESULTS: This study gives a plausible bio...

詳細記述

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書誌詳細
出版年:BMC Syst Biol
主要な著者: Wu, Wei-Sheng, Lai, Fu-Jou
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674858/
https://ncbi.nlm.nih.gov/pubmed/26678747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-9-S6-S2
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