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Amyloidogenic oligomerization transforms Drosophila Orb2 from a translation repressor to an activator

Memories are thought to be formed in response to transient experiences in part through changes in local protein synthesis at synapses. In Drosophila, the amyloidogenic (prion-like) state of the RNA binding protein Orb2 has been implicated in long-term memory, but how conformational conversion of Orb...

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Podrobná bibliografie
Vydáno v:Cell
Hlavní autoři: Khan, Mohammed ‘Repon’, Li, Liying, Pérez-Sánchez, Consuelo, Saraf, Anita, Florens, Laurence, Slaughter, Brian D., Unruh, Jay R., Si, Kausik
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674814/
https://ncbi.nlm.nih.gov/pubmed/26638074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.020
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