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Amyloidogenic oligomerization transforms Drosophila Orb2 from a translation repressor to an activator
Memories are thought to be formed in response to transient experiences in part through changes in local protein synthesis at synapses. In Drosophila, the amyloidogenic (prion-like) state of the RNA binding protein Orb2 has been implicated in long-term memory, but how conformational conversion of Orb...
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| Pubblicato in: | Cell |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674814/ https://ncbi.nlm.nih.gov/pubmed/26638074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.020 |
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