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Amyloidogenic oligomerization transforms Drosophila Orb2 from a translation repressor to an activator
Memories are thought to be formed in response to transient experiences in part through changes in local protein synthesis at synapses. In Drosophila, the amyloidogenic (prion-like) state of the RNA binding protein Orb2 has been implicated in long-term memory, but how conformational conversion of Orb...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674814/ https://ncbi.nlm.nih.gov/pubmed/26638074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.020 |
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