Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation

Amyloids are ordered protein aggregates that are typically associated with neurodegenerative diseases and cognitive impairment. By contrast, the amyloid-like state of the neuronal RNA binding protein Orb2 in Drosophila was recently implicated in memory consolidation, but it remains unclear what feat...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Hervás, Rubén, Li, Liying, Majumdar, Amitabha, Fernández-Ramírez, María del Carmen, Unruh, Jay R., Slaughter, Brian D., Galera-Prat, Albert, Santana, Elena, Suzuki, Mari, Nagai, Yoshitaka, Bruix, Marta, Casas-Tintó, Sergio, Menéndez, Margarita, Laurents, Douglas V., Si, Kausik, Carrión-Vázquez, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727891/
https://ncbi.nlm.nih.gov/pubmed/26812143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002361
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