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Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress

Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved enzyme in the NAD synthetic pathway. It has also been identified as an effective and versatile neuroprotective factor. However, it remains unclear how healthy neurons regulate the dual functions of NMNAT and achieve self-protecti...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ruan, Kai, Zhu, Yi, Li, Chong, Brazill, Jennifer M., Zhai, R. Grace
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674693/
https://ncbi.nlm.nih.gov/pubmed/26616331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10057
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