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Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is the major dose-limiting side effect of many commonly used chemotherapeutic agents, including paclitaxel. Currently, there are no neuroprotective or effective symptomatic treatments for CIPN. Lack of understanding of the in vivo mechanisms of CIPN...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Brazill, Jennifer M., Cruz, Beverley, Zhu, Yi, Zhai, R. Grace
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031360/
https://ncbi.nlm.nih.gov/pubmed/29716954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032938
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