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Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is the major dose-limiting side effect of many commonly used chemotherapeutic agents, including paclitaxel. Currently, there are no neuroprotective or effective symptomatic treatments for CIPN. Lack of understanding of the in vivo mechanisms of CIPN...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Brazill, Jennifer M., Cruz, Beverley, Zhu, Yi, Zhai, R. Grace
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031360/
https://ncbi.nlm.nih.gov/pubmed/29716954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032938
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