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Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress

Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved enzyme in the NAD synthetic pathway. It has also been identified as an effective and versatile neuroprotective factor. However, it remains unclear how healthy neurons regulate the dual functions of NMNAT and achieve self-protecti...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Ruan, Kai, Zhu, Yi, Li, Chong, Brazill, Jennifer M., Zhai, R. Grace
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674693/
https://ncbi.nlm.nih.gov/pubmed/26616331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10057
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