Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) is a powerful tool to evaluate malaria vaccine and prophylactic drug efficacy. Until recently CHMI was only carried out by the bite of infected mosquitoes. A parenteral method of CHMI would standardize Plasmodium falciparum sporozoite (PfSPZ) administration,...

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Vydáno v:Am J Trop Med Hyg
Hlavní autoři: Lyke, Kirsten E., Laurens, Matthew B., Strauss, Kathy, Adams, Matthew, Billingsley, Peter F., James, Eric, Manoj, Anita, Chakravarty, Sumana, Plowe, Christopher V., Li, Ming Lin, Ruben, Adam, Edelman, Robert, Green, Michael, Dube, Tina J., Kim Lee Sim, B., Hoffman, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674246/
https://ncbi.nlm.nih.gov/pubmed/26416102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0341
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