Plasmodium falciparum Malaria Challenge by the Bite of Aseptic Anopheles stephensi Mosquitoes: Results of a Randomized Infectivity Trial

BACKGROUND: Experimental infection of malaria-naïve volunteers by the bite of Plasmodium falciparum-infected mosquitoes is a preferred means to test the protective effect of malaria vaccines and drugs. The standard model relies on the bite of five infected mosquitoes to induce malaria. We examined t...

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Bibliographic Details
Main Authors: Lyke, Kirsten E., Laurens, Matthew, Adams, Matthew, Billingsley, Peter F., Richman, Adam, Loyevsky, Mark, Chakravarty, Sumana, Plowe, Christopher V., Sim, B. Kim Lee, Edelman, Robert, Hoffman, Stephen L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958836/
https://ncbi.nlm.nih.gov/pubmed/21042404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013490
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