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Successful Human Infection with P. falciparum Using Three Aseptic Anopheles stephensi Mosquitoes: A New Model for Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) is a powerful method for assessing the efficacy of anti-malaria vaccines and drugs targeting pre-erythrocytic and erythrocytic stages of the parasite. CHMI has heretofore required the bites of 5 Plasmodium falciparum (Pf) sporozoite (SPZ)-infected mosquitoes...

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Dettagli Bibliografici
Autori principali: Laurens, Matthew B., Billingsley, Peter, Richman, Adam, Eappen, Abraham G., Adams, Matthew, Li, Tao, Chakravarty, Sumana, Gunasekera, Anusha, Jacob, Christopher G., Sim, B. Kim Lee, Edelman, Robert, Plowe, Christopher V., Hoffman, Stephen L., Lyke, Kirsten E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712927/
https://ncbi.nlm.nih.gov/pubmed/23874828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068969
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