Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) is a powerful tool to evaluate malaria vaccine and prophylactic drug efficacy. Until recently CHMI was only carried out by the bite of infected mosquitoes. A parenteral method of CHMI would standardize Plasmodium falciparum sporozoite (PfSPZ) administration,...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Lyke, Kirsten E., Laurens, Matthew B., Strauss, Kathy, Adams, Matthew, Billingsley, Peter F., James, Eric, Manoj, Anita, Chakravarty, Sumana, Plowe, Christopher V., Li, Ming Lin, Ruben, Adam, Edelman, Robert, Green, Michael, Dube, Tina J., Kim Lee Sim, B., Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674246/
https://ncbi.nlm.nih.gov/pubmed/26416102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0341
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