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A Hypothesis Concerning the Biphasic Dose-response of Tumors to Angiostatin and Endostatin
This manuscript proposes a hypothesis to explain the U-shaped dose-response observed for angiostatin and other high-molecular-weight drugs in various anti-cancer bio-assays. The dose-response curves for angiostatin and endostatin (measured as suppression of tumor growth) go through an optimum (i.e.,...
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| Publicado no: | Dose Response |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674172/ https://ncbi.nlm.nih.gov/pubmed/26675544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2203/dose-response.14-020.Parris |
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