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HYDROXYUREA TREATMENT DECREASES GLOMERULAR HYPERFILTRATION IN CHILDREN WITH SICKLE CELL ANEMIA

BACKGROUND: Glomerular hyperfiltration and microalbuminuria/proteinuria are early manifestations of sickle nephropathy. The effects of hydroxyurea therapy on these renal manifestations of sickle cell anemia (SCA) are not well defined. OBJECTIVE: To investigate the effects of hydroxyurea on glomerula...

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Detalhes bibliográficos
Publicado no:Am J Hematol
Main Authors: Aygun, Banu, Mortier, Nicole A., Smeltzer, Matthew P., Shulkin, Barry L., Hankins, Jane S., Ware, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673980/
https://ncbi.nlm.nih.gov/pubmed/23255310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23365
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