Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation

Apoptosis resistance in activated neutrophils is known to be associated with collateral damage of surrounding tissue, as well as immune and organ dysfunction. Thus, the safe removal of neutrophils by apoptosis induction represents a prerequisite for the resolution of inflammation. Here, we report th...

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Bibliografische gegevens
Gepubliceerd in:J Leukoc Biol
Hoofdauteurs: Hornstein, Tamara, Lehmann, Sarah, Philipp, Denise, Detmer, Susanne, Hoffmann, Michèle, Peter, Christoph, Wesselborg, Sebastian, Unfried, Klaus, Windolf, Joachim, Flohé, Sascha, Paunel-Görgülü, Adnana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Leukocyte Biology 2016
Onderwerpen:
Inflammation, Extracellular Mediators, & Effector Molecules
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673481/
https://ncbi.nlm.nih.gov/pubmed/26310832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1114-537RR
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