Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation

Apoptosis resistance in activated neutrophils is known to be associated with collateral damage of surrounding tissue, as well as immune and organ dysfunction. Thus, the safe removal of neutrophils by apoptosis induction represents a prerequisite for the resolution of inflammation. Here, we report th...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Hornstein, Tamara, Lehmann, Sarah, Philipp, Denise, Detmer, Susanne, Hoffmann, Michèle, Peter, Christoph, Wesselborg, Sebastian, Unfried, Klaus, Windolf, Joachim, Flohé, Sascha, Paunel-Görgülü, Adnana
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2016
Subjects:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673481/
https://ncbi.nlm.nih.gov/pubmed/26310832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1114-537RR
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