Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation

Apoptosis resistance in activated neutrophils is known to be associated with collateral damage of surrounding tissue, as well as immune and organ dysfunction. Thus, the safe removal of neutrophils by apoptosis induction represents a prerequisite for the resolution of inflammation. Here, we report th...

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Detaylı Bibliyografya
Yayımlandı:J Leukoc Biol
Asıl Yazarlar: Hornstein, Tamara, Lehmann, Sarah, Philipp, Denise, Detmer, Susanne, Hoffmann, Michèle, Peter, Christoph, Wesselborg, Sebastian, Unfried, Klaus, Windolf, Joachim, Flohé, Sascha, Paunel-Görgülü, Adnana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Leukocyte Biology 2016
Konular:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673481/
https://ncbi.nlm.nih.gov/pubmed/26310832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1114-537RR
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