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Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation

Apoptosis resistance in activated neutrophils is known to be associated with collateral damage of surrounding tissue, as well as immune and organ dysfunction. Thus, the safe removal of neutrophils by apoptosis induction represents a prerequisite for the resolution of inflammation. Here, we report th...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Hornstein, Tamara, Lehmann, Sarah, Philipp, Denise, Detmer, Susanne, Hoffmann, Michèle, Peter, Christoph, Wesselborg, Sebastian, Unfried, Klaus, Windolf, Joachim, Flohé, Sascha, Paunel-Görgülü, Adnana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673481/
https://ncbi.nlm.nih.gov/pubmed/26310832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A1114-537RR
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