Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway

Hyperglycemia-induced reactive oxygen species (ROS) generation and Ca(2+) overload contribute to the development of diabetic cardiomyopathy. In this study, we aimed to study the protective effects of Chikusetsu saponin IVa (CHS) from Aralia taibaiensis against hyperglycemia-induced myocardial injuri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Duan, Jialin, Yin, Ying, Wei, Guo, Cui, Jia, Zhang, Enhu, Guan, Yue, Yan, Jiajia, Guo, Chao, Zhu, Yanrong, Mu, Fei, Weng, Yan, Wang, Yanhua, Wu, Xiaoxiao, Xi, Miaomiao, Wen, Aidong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673450/
https://ncbi.nlm.nih.gov/pubmed/26648253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18123
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