Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway

Islet β cell mass reduction induced by glucose fluctuation is crucial for the development and progression of T2DM. Chikusetsu saponin IVa (CHS) had protective effects against DM and related injuries. Here we aimed to investigate the role of CHS in β cell injuries and its possible mechanism involved....

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Cui, Jia, Duan, Jialin, Chu, Jianjie, Guo, Chao, Xi, Miaomiao, Li, Yi, Weng, Yan, Wei, Guo, Yin, Ying, Wen, Aidong, Qiao, Boling
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053639/
https://ncbi.nlm.nih.gov/pubmed/31969494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102702
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