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Chikusetsu saponin IVa attenuates isoflurane-induced neurotoxicity and cognitive deficits via SIRT1/ERK1/2 in developmental rats

Inhalation anesthetics isoflurane may increase the risk of neurotoxicity and cognitive deficiency at postnatal and childhood. Chikusetsu saponin IVa (chIV) is a plant extract compound, which could possessed extensive pharmacological actions of central nervous system, cardia-cerebrovascular system, i...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Fang, Xi, Han, Qiang, Li, Shiyong, Zhao, Yilin, Luo, Ailin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622271/
https://ncbi.nlm.nih.gov/pubmed/28979702
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