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MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function
The protein p73, a homologue of the tumor suppressor protein p53, is capable of inducing apoptosis and cell cycle arrest. MDM2 is transcriptionally activated by p73 and represses the functions of p73, including p73-dependent transactivation and growth suppression. However, the molecular mechanism of...
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| 出版年: | Oncotarget |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673280/ https://ncbi.nlm.nih.gov/pubmed/26025930 |
| タグ: |
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