Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis

Bone Morphogenetic Proteins (BMPs) are secreted cytokines/growth factors belonging to the Transforming Growth Factor β (TGFβ) family. BMP ligands have been shown to be overexpressed in human breast cancers. Normal and cancerous breast tissue display active BMP signaling as indicated by phosphorylate...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Pickup, Michael W., Hover, Laura D., Guo, Yan, Gorska, Agnieszka E., Chytil, Anna, Novitskiy, Sergey V., Moses, Harold L., Owens, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673207/
https://ncbi.nlm.nih.gov/pubmed/26274893
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