Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells

B-cell chronic lymphocytic leukemia (CLL) was believed to result from clonal accumulation of resting apoptosis-resistant malignant B lymphocytes. However, it became increasingly clear that CLL cells undergo, during their life, iterative cycles of re-activation and subsequent clonal expansion. Drugs...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bruno, Silvia, Ledda, Bernardetta, Tenca, Claudya, Ravera, Silvia, Orengo, Anna Maria, Mazzarello, Andrea Nicola, Pesenti, Elisa, Casciaro, Salvatore, Racchi, Omar, Ghiotto, Fabio, Marini, Cecilia, Sambuceti, Gianmario, DeCensi, Andrea, Fais, Franco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673187/
https://ncbi.nlm.nih.gov/pubmed/26265439
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