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Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements

In Drosophila, Polycomb (PcG) and Trithorax (TrxG) group proteins are assembled on Polycomb response elements (PREs) to maintain tissue and stage-specific patterns of gene expression. Critical to coordinating gene expression with the process of differentiation, the activity of PREs can be switched “...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Erokhin, Maksim, Elizar’ev, Pavel, Parshikov, Aleksander, Schedl, Paul, Georgiev, Pavel, Chetverina, Darya
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672805/
https://ncbi.nlm.nih.gov/pubmed/26504232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515276112
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