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Making connections: Insulators organize eukaryotic chromosomes into independent cis-regulatory networks

Insulators play a central role in subdividing the chromosome into a series of discrete topologically independent domains and in ensuring that enhancers and silencers contact their appropriate target genes. In this review we first discuss the general characteristics of insulator elements and their as...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Chetverina, Darya, Aoki, Tsutomu, Erokhin, Maksim, Georgiev, Pavel, Schedl, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362772/
https://ncbi.nlm.nih.gov/pubmed/24277632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300125
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