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Making connections: Insulators organize eukaryotic chromosomes into independent cis-regulatory networks

Insulators play a central role in subdividing the chromosome into a series of discrete topologically independent domains and in ensuring that enhancers and silencers contact their appropriate target genes. In this review we first discuss the general characteristics of insulator elements and their as...

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Bibliografske podrobnosti
izdano v:Bioessays
Main Authors: Chetverina, Darya, Aoki, Tsutomu, Erokhin, Maksim, Georgiev, Pavel, Schedl, Paul
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362772/
https://ncbi.nlm.nih.gov/pubmed/24277632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300125
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