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Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements

In Drosophila, Polycomb (PcG) and Trithorax (TrxG) group proteins are assembled on Polycomb response elements (PREs) to maintain tissue and stage-specific patterns of gene expression. Critical to coordinating gene expression with the process of differentiation, the activity of PREs can be switched “...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Erokhin, Maksim, Elizar’ev, Pavel, Parshikov, Aleksander, Schedl, Paul, Georgiev, Pavel, Chetverina, Darya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672805/
https://ncbi.nlm.nih.gov/pubmed/26504232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515276112
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