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Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements

In Drosophila, Polycomb (PcG) and Trithorax (TrxG) group proteins are assembled on Polycomb response elements (PREs) to maintain tissue and stage-specific patterns of gene expression. Critical to coordinating gene expression with the process of differentiation, the activity of PREs can be switched “...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Erokhin, Maksim, Elizar’ev, Pavel, Parshikov, Aleksander, Schedl, Paul, Georgiev, Pavel, Chetverina, Darya
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672805/
https://ncbi.nlm.nih.gov/pubmed/26504232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515276112
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