Učitavanje...
Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicing
RNA polymerase II (RNAPII) transcription elongation is a highly regulated process that greatly influences mRNA levels as well as pre-mRNA splicing. Despite many studies in vitro, how chromatin modulates RNAPII elongation in vivo is still unclear. Here, we show that a decrease in the level of availab...
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Izdano u: | Proc Natl Acad Sci U S A |
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Glavni autori: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
National Academy of Sciences
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672771/ https://ncbi.nlm.nih.gov/pubmed/26578803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506760112 |
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