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Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

Various histone modifications decorate nucleosomes within transcribed genes. Among these, monoubiquitylation of histone H2B (H2Bub1) and methylation of histone H3 on lysines 36 (H3K36me2/3) and 79 (H3K79me2/3) correlate positively with gene expression. By measuring the progression of the transcripti...

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Detalhes bibliográficos
Main Authors: Fuchs, Gilad, Hollander, Dror, Voichek, Yoav, Ast, Gil, Oren, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199367/
https://ncbi.nlm.nih.gov/pubmed/25049226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.176487.114
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