Načítá se...

Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction

BACKGROUND: This study aimed at developing nerve growth factor (NGF) mimetics that selectively activate specific biological signals and, as a result, lack the side effects of the full-length protein. Two dimeric dipeptides, bis-(N-aminocaproyl-glycyl-L-lysine) hexamethylenediamide (GK-6) and bis(N-s...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	J Biomed Sci
Hlavní autoři:	Gudasheva, Tatyana A., Povarnina, Polina Yu, Antipova, Tatyana A., Firsova, Yulia N., Konstantinopolsky, Mark A., Seredenin, Sergey B.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BioMed Central 2015
Témata:	Research
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4672491/ https://ncbi.nlm.nih.gov/pubmed/26642930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0198-z
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo otaguje tento záznam!

Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction

Podobné jednotky