Dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4 are active in a model of ischemic stroke

Pharmacological activity of dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4, correspondingly GTS-115 and GK-2, was studied in a model of ischemic stroke, induced by transient middle cerebral artery occlusion in rats. The both compounds, at i.p. subchronic administration (0,5-1 mg...

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Bibliografiske detaljer

Principais autores:	P. Y. Povarnina, T. A. Gudasheva, S. B. Seredenin
Format:	Artigo
Sprog:	Russo
Udgivet:	LLC “Publisher OKI” 2016-09-01
Serier:	Фармакокинетика и Фармакодинамика
Fag:	димерный дипептидный миметик фактор роста нервов нейропротекция ишемический инсульт окклюзия средней мозговой артерии dimeric dipeptide mimetic nerve growth factor neuroprotection ischemic stroke middle cerebral artery occlusion
Online adgang:	https://www.pharmacokinetica.ru/jour/article/view/182
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