Dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4 are active in a model of ischemic stroke

Pharmacological activity of dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4, correspondingly GTS-115 and GK-2, was studied in a model of ischemic stroke, induced by transient middle cerebral artery occlusion in rats. The both compounds, at i.p. subchronic administration (0,5-1 mg...

ver descrição completa

Detalhes bibliográficos

Principais autores:	P. Y. Povarnina, T. A. Gudasheva, S. B. Seredenin
Formato:	Artigo
Idioma:	Russo
Publicado em:	LLC “Publisher OKI” 2016-09-01
coleção:	Фармакокинетика и Фармакодинамика
Assuntos:	димерный дипептидный миметик фактор роста нервов нейропротекция ишемический инсульт окклюзия средней мозговой артерии dimeric dipeptide mimetic nerve growth factor neuroprotection ischemic stroke middle cerebral artery occlusion
Acesso em linha:	https://www.pharmacokinetica.ru/jour/article/view/182
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!