Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors

Kdm3b is a JmjC domain-containing histone H3 (H3) demethylase and its physiological functions are largely unknown. In this study, we found that Kdm3b protein is highly expressed in multiple cell types in the mouse testes, including Leydig cells, Sertoli cells, spermatogonia and spermatocytes at diff...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Liu, Zhaoliang, Oyola, Mario G., Zhou, Suoling, Chen, Xian, Liao, Lan, Tien, Jean Ching-Yi, Mani, Shailaja K., Xu, Jianming
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672002/
https://ncbi.nlm.nih.gov/pubmed/26681924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13795
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