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Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors

Kdm3b is a JmjC domain-containing histone H3 (H3) demethylase and its physiological functions are largely unknown. In this study, we found that Kdm3b protein is highly expressed in multiple cell types in the mouse testes, including Leydig cells, Sertoli cells, spermatogonia and spermatocytes at diff...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Liu, Zhaoliang, Oyola, Mario G., Zhou, Suoling, Chen, Xian, Liao, Lan, Tien, Jean Ching-Yi, Mani, Shailaja K., Xu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672002/
https://ncbi.nlm.nih.gov/pubmed/26681924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13795
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