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Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors

Kdm3b is a JmjC domain-containing histone H3 (H3) demethylase and its physiological functions are largely unknown. In this study, we found that Kdm3b protein is highly expressed in multiple cell types in the mouse testes, including Leydig cells, Sertoli cells, spermatogonia and spermatocytes at diff...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Liu, Zhaoliang, Oyola, Mario G., Zhou, Suoling, Chen, Xian, Liao, Lan, Tien, Jean Ching-Yi, Mani, Shailaja K., Xu, Jianming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672002/
https://ncbi.nlm.nih.gov/pubmed/26681924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13795
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