Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia

The aims of this study are to clarify the role of mTOR in mediating cerebral ischemic brain damage and the effects of rapamycin on ischemic outcomes. Ten minutes of forebrain ischemia was induced in rats, and their brains were sampled after 3 h, 16 h, and 7 days reperfusion for histology, immunohist...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Biol Sci
Main Authors: Yang, Xiao, Hei, Changhun, Liu, Ping, Song, Yaozu, Thomas, Taylor, Tshimanga, Sylvie, Wang, Feng, Niu, Jianguo, Sun, Tao, Li, P. Andy
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672000/
https://ncbi.nlm.nih.gov/pubmed/26681922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12930
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