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Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia

The aims of this study are to clarify the role of mTOR in mediating cerebral ischemic brain damage and the effects of rapamycin on ischemic outcomes. Ten minutes of forebrain ischemia was induced in rats, and their brains were sampled after 3 h, 16 h, and 7 days reperfusion for histology, immunohist...

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Publicat a:Int J Biol Sci
Autors principals: Yang, Xiao, Hei, Changhun, Liu, Ping, Song, Yaozu, Thomas, Taylor, Tshimanga, Sylvie, Wang, Feng, Niu, Jianguo, Sun, Tao, Li, P. Andy
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672000/
https://ncbi.nlm.nih.gov/pubmed/26681922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12930
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