Profiling the role of mammalian target of rapamycin in the vascular smooth muscle metabolome in pulmonary arterial hypertension

Abstract. Increased proliferation and resistance to apoptosis of pulmonary arterial vascular smooth muscle cells (PAVSMCs), coupled with metabolic reprogramming, are key components of pulmonary vascular remodeling, a major and currently irreversible pathophysiological feature of pulmonary arterial h...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Kudryashova, Tatiana V., Goncharov, Dmitry A., Pena, Andressa, Ihida-Stansbury, Kaori, DeLisser, Horace, Kawut, Steven M., Goncharova, Elena A.
Formato: Artigo
Idioma:Inglês
Publicado em: University of Chicago Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671741/
https://ncbi.nlm.nih.gov/pubmed/26697174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/683810
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