HIPPO–Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension

Rationale: Enhanced proliferation and impaired apoptosis of pulmonary arterial vascular smooth muscle cells (PAVSMCs) are key pathophysiologic components of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). Objectives: To determine the role and therapeutic relevance of HIPPO si...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Crit Care Med
Hoofdauteurs: Kudryashova, Tatiana V., Goncharov, Dmitry A., Pena, Andressa, Kelly, Neil, Vanderpool, Rebecca, Baust, Jeff, Kobir, Ahasanul, Shufesky, William, Mora, Ana L., Morelli, Adrian E., Zhao, Jing, Ihida-Stansbury, Kaori, Chang, Baojun, DeLisser, Horace, Tuder, Rubin M., Kawut, Steven M., Silljé, Herman H. W., Shapiro, Steven, Zhao, Yutong, Goncharova, Elena A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074651/
https://ncbi.nlm.nih.gov/pubmed/27119551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201510-2003OC
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