mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia

Pulmonary arterial vascular smooth muscle (PAVSM) cell proliferation is a key pathophysiological component of vascular remodeling in pulmonary arterial hypertension (PAH) for which cellular and molecular mechanisms are poorly understood. The goal of our study was to determine the role of mammalian t...

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Detalhes bibliográficos
Main Authors: Krymskaya, Vera P., Snow, Jennifer, Cesarone, Gregory, Khavin, Irene, Goncharov, Dmitry A., Lim, Poay N., Veasey, Sigrid C., Ihida-Stansbury, Kaori, Jones, Peter L., Goncharova, Elena A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101038/
https://ncbi.nlm.nih.gov/pubmed/21368105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-175018
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